Pure TMG (60 capsules)

Support Methylation, Protect DNA, and Strengthen Cellular Health at Every Level.

60 capsules

Relentless Research. Unmatched Purity. Sharpen Your Mind and Slow Aging at the Cellular Level

 

At DoNotAge.org, we are not a supplement brand, we are a Health Research Organisation. Our mission is to fund studies, conduct in-house research, and deliver clinically relevant ingredients used by scientists leading global health research.

 

Pure TMG is no exception. Sourced, tested, and verified in-house to meet the highest research standards, it plays a critical role in supporting methylation, an essential biological process that helps maintain DNA integrity, cardiovascular health, and overall cellular function.

 

While most companies prioritise profit, we prioritise science. That is why Pure TMG is used by researchers, scientists, and health experts who require uncompromising purity and real-world results, not marketing hype.

 

• Supports Methylation – Vital for DNA repair, cellular function, and optimal gene expression
• Promotes Liver Health – Encourages detoxification and fat metabolism
• Balances Homocysteine – Supports heart health and vascular function
• Enhances Cognitive Function – Aids neurotransmitter production and brain health
• Protects Cellular Energy – Helps maintain healthy mitochondria for lasting vitality

 

No fillers. No shortcuts. No compromises. Just research-leading TMG, rigorously tested and used by experts driving the science of healthy aging.

 

When it comes to your health, quality is not optional, it is essential. Experience the DoNotAge.org difference. Choose Pure TMG

 

BENEFITS OF PURE TMG

 

✔ Supports Methylation & DNA Repair – Provides essential methyl groups that power DNA repair, gene expression, and healthy cellular function.*

 

✔ Promotes Heart & Vascular Health – Helps balance homocysteine levels, a key factor in cardiovascular health and longevity.*

 

✔ Enhances Liver Function & Detoxification – Supports liver health, fat metabolism, and efficient detoxification pathways.*

 

✔ Optimizes Cognitive Function & Mental Clarity – Aids neurotransmitter production for sharper focus, memory, and cognitive performance.*

 

✔ Protects Cellular Energy Production – Supports mitochondrial health to maintain lasting energy at the cellular level.*

 

✔ Promotes Healthy Aging & Longevity – Protects cells from methylation imbalances that accelerate aging and functional decline.*

 

✔ Synergistic Longevity Support – Complements NMN and other longevity compounds by maintaining methylation balance for optimal results.*

PRODUCT DETAILS

 

✔ Highest Purity Trimethylglycine (TMG) – Ultra-pure, scientifically validated, and free from fillers or additives.

 

✔ Supports Essential Methylation Pathways – Critical for DNA repair, detoxification, heart health, and cognitive performance.*

 

✔ Clinically Relevant Dosing – Formulated for maximum effectiveness based on scientific research and biological requirements.

 

✔ Vegan & Non-GMO – Contains no artificial ingredients, preservatives, or animal byproducts.

 

✔ Third-Party & In-House Tested – Rigorously verified for purity, potency, and research-leading quality standards.

The Science Behind Pure TMG

 

Aging isn’t just a matter of time,  it’s the gradual breakdown of your body’s core cellular processes. One of the most overlooked, yet essential, is methylation: the biological mechanism that keeps your DNA stable, your liver functioning, and your heart protected.

 

At DoNotAge.org, we are a Health Research Organisation, not a supplement brand. We conduct and fund global research into clinically relevant compounds like Trimethylglycine (TMG) and formulate only the purest versions for scientific application and human health. Every ingredient we offer is tested in-house, used by researchers, and meets the highest research standards, not marketing hype.

 

Why Methylation Matters

 

Methylation is your body’s internal engine for DNA repair, detoxification, neurotransmitter production, and cardiovascular protection. Without it, cells degrade faster, inflammation builds, and homocysteine, a harmful amino acid rises, increasing your risk of heart and liver problems.

 

Trimethylglycine (TMG) is a key methyl donor. It provides the essential methyl groups your body needs to power these critical biological reactions, keeping your cells resilient and your systems functioning properly.

 

What the Science Says

 

TMG has been widely studied for its impact on methylation support, homocysteine regulation, and liver health. It is frequently used by researchers in clinical trials and is valued for its ability to:

 

• Lower homocysteine levels – supporting heart and vascular health
• Improve liver fat metabolism and detox efficiency
• Promote DNA methylation for gene regulation and repair
• Support neurotransmitter production for mental clarity and mood balance
• Preserve mitochondrial health and energy generation

 

TMG is especially important for those taking longevity compounds like NMN, which may increase methylation demand. By maintaining proper methyl group availability, Pure TMG helps the body perform at its best at any age.

 

A Scientific Breakthrough in Longevity

 

At DoNotAge.org, we collaborate directly with leading scientists and health researchers to develop and validate ingredients that support the body’s most essential biological functions. Pure TMG is a result of that mission, a research-leading compound known for its role in powering methylation, protecting DNA, and maintaining heart and liver function.

 

Studies show that maintaining adequate methylation through TMG supplementation can:

 

✔ Support cardiovascular health by reducing elevated homocysteine levels

✔ Enhance liver detoxification and protect against fatty liver accumulation

✔ Promote DNA stability through improved methyl group availability

✔ Support neurotransmitter synthesis for improved mood and cognitive function

 

Our commitment goes beyond simply extending lifespan. It’s about improving healthspan & helping your body stay strong, balanced, and biologically resilient at every stage of life.

 

Scientific References & Studies:

• Low Dose Betaine Supplementation Leads to Immediate and Long Term Lowering of Plasma Homocysteine in Healthy Men and Women | The Journal of Nutrition | Oxford Academic
• Betaine attenuates chronic alcohol‑induced fatty liver by broadly regulating hepatic lipid metabolism
• Effect of betaine supplementation on power performance and fatigue – PMC
• Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study
• Article Betaine, ethanol, and the liver: A review
• Effects of betaine on body composition, performance, and homocysteine thiolactone – PMC
• Betaine in Inflammation: Mechanistic Aspects and Applications – PMC

 

Pure TMG is part of our greater mission to deliver science-led, biologically essential compounds that support healthier aging from the inside out. With research-leading purity and a critical role in DNA repair, liver function, and cardiovascular health, Pure TMG helps maintain the core processes your body relies on to stay strong and resilient.

 

Join us in advancing human health through science. Try Pure TMG and experience what targeted methylation support can do for your body.

 

Alan Graves
Founder & Clinical Research Advisor
DoNotAge.org

 

*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure, or prevent any disease.

 

 

Trimethylglycine (TMG) – Methylation, DNA Support & Cardiovascular Health

 

At DoNotAge.org, we don’t follow longevity science, we help lead it. Pure TMG is a research-leading form of Trimethylglycine, trusted by scientists and practitioners for its critical role in methylation, liver detoxification, and homocysteine balance. Unlike many TMG supplements that include unnecessary fillers or lack purity validation, we rigorously test every batch to ensure uncompromising quality and clinical relevance.

 

TMG is a powerful methyl donor and it supplies the body with essential methyl groups needed for DNA repair, liver function, neurotransmitter production, and heart health. When methylation is impaired, it can contribute to DNA instability, cognitive decline, and elevated homocysteine, a risk factor for cardiovascular disease.

 

Scientific research shows that supplementing with TMG can help:

 

✔ Support DNA Methylation – Maintains healthy gene expression and cellular repair.*
✔ Balance Homocysteine – Helps reduce cardiovascular risk and support vascular health.*
✔ Promote Liver Detoxification – Supports fat metabolism and natural detox pathways.*
✔ Enhance Brain Function – Aids neurotransmitter production for focus and mood balance.*
✔ Preserve Cellular Energy – Supports mitochondrial function and biological resilience.*

 

Not all TMG is created equal. If you care about your health, choose TMG that meets research standards; no fillers, no shortcuts, just real science.

 

At DoNotAge.org, our commitment is to deliver compounds in their most bioavailable, clinically relevant form, helping you protect your cells and support long-term vitality through targeted, science-led solutions.

Pure TMG Capsules – Clean, Research-Leading Methylation Support

Our Pure TMG capsules contain highly purified Trimethylglycine (Betaine Anhydrous), encapsulated in Hypromellose (HPMC) vegetable cellulose, a plant-based, vegan-friendly alternative to gelatin. Each capsule delivers targeted methylation support in a convenient, easy-to-take form.

 

✔ Non-GMO & Allergen-Free – No synthetic fillers, preservatives, or artificial ingredients.*

✔ Bioavailable & Effective – Formulated for optimal absorption and biological activity.*

✔ Gentle on the Digestive System – Suitable for sensitive individuals.*

✔ Vegan & Clean Label – Free from animal byproducts and unnecessary additives.*

The DoNotAge.org Quality Guarantee

 

Pure TMG comes with the DoNotAge.org Quality Guarantee, ensuring every bottle meets the highest standards for purity, safety, and scientific integrity, from our facility to your doorstep.

 

✔ Produced to GMP and ISO9001 Standards – Manufactured under globally recognised quality systems for consistency and excellence.*

✔ Science-Led & Rigorously Tested – Each batch is independently and internally tested for purity, potency, and performance.*

✔ Full Usage Instructions Included – Your order arrives with easy-to-follow guidance for best results.*

✔ 100% Vegan & Clean – Free from animal products, artificial additives, and unnecessary fillers.*

 

At DoNotAge.org, we are committed to delivering research-led solutions that help people live longer, healthier lives. Pure TMG reflects our mission to support healthy aging by offering targeted, clinically relevant compounds backed by science, not marketing.